CNS*2011 Workshop: "Basal Ganglia: Dynamics, Function and Learning"
Organisers
• Arvind Kumar (Neurobiology and Biophysics, Faculty of Biology and BCF, University of Freiburg, Germany)
• Jeanette Hellgren Kotaleski (Royal Institute of Technology, Stockholm, Sweden)
• Dieter Jaeger (Department of Biology, Emory University, Atlanta, USA)
Topic description
The basal ganglia (BG) are involved in a wide range of motor and cognitive processes, and accordingly, their dysfunction can lead to several neurological diseases. Extensive experimental characterization at multiple scales of the BG in normal and pathological conditions have provided important insights about the BG. However, a coherent computational theory linking these observations to function has eluded the neuroscientists.
Bottom-up computational approaches have addressed the dynamical properties and interaction of the neural activity in the BG nuclei, while top-down approaches rather have described BG function inspired by machine learning algorithms.
In this workshop, we will discuss progress made in our understanding of the BG at multiple scales with the aim to bridge between bottom-up and top-down approaches. The main emphasis of the workshop will be to understand how the dynamics relate to function and dysfunction of BG. In addition, the workshop will foster an interaction between experimentalists and theoreticians.
Final Program
|
Speaker |
Title |
|
The basal ganglia - introduction: 0915 – 0945 (chair: Dieter Jaeger) |
|
|
Jeanette Hellgren Kotaleski/ Sten Grillner The Nobel Institute for Neurophysiology, Karolinska Institutet, Stockholm, Sweden |
Evolutionary perspectives of the basal ganglia |
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Cellular- and subcellular properties of basal ganglia neurons: 0945 – 1045 (chair: Jeanette Hellgren Kotaleski) |
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|
Carmen Canvier LSUHSC Neuroscience Center of Excellence, New Oreleons, USA |
Using the dynamic clamp combined with computational models to determine how the spiking rate is controlled in SNC dopamine neurons
|
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Avrama Blackwell George Mason University, Fairfax, VA, USA |
Modeling the role of temporal pattern and subcellular location in synaptic plasticity
|
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Basal ganglia microcircuits: 1100 – 1230 (chair: Arvind Kumar) |
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|
Charles Wilson University of Texas, San Antonio, TX, USA |
A second type of tonically active neurons in the striatum.
|
|
Dieter Jaeger Emory University, Atlanta, US |
Modeling synaptic integration in Globus Pallidus neurons |
|
Gilad Silberberg The Nobel Institute for Neurophysiology, Stockholm, Sweden |
Intrastriatal connectivity: what we think we know, and what we don't |
|
Basal ganglia network: 1400 – 1600 (chair: Dieter Jaeger) |
|
|
Izhar Bar-Gad Gonda Brain Research Center, Bar-Ilan University, Israel |
Decorrelation breakdown in the abnormal basal ganglia |
|
Arvind Kumar University of Freiburg, Germany |
Origin of oscillations in the basal ganglia: Implication for deep brain stimulation |
|
Kevin Gurney The University of Sheffield, Sheffield, UK |
Cortico-striatal plasticity for action learning using spike timing dependent eligibility
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|
Abigail Morrison University of Freiburg, Germany |
Limits of dopamine-modulated cortico-striatal plasticity as a substrate for temporal-difference learning |
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Applications of BG models: 1615 – 1745 (chair: Christian Hauptmann & Peter Tass) |
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|
Stephane van Gils Nonlinear Analysis Department of Mathematics University of Twente, The Netherlands
Jean-Pascal Pfister Computational Neuroscience Lab, Physiology Department, Univ of Bern, Switzerland
Christian Hauptmann & Peter Tass Institute for Neuroscience and Medicine – Neuromodulation, Research Center Jülich, Germany
|
From parkinsonian thalamic activity to restoring thalamic relay using Deep Brain Stimulation: new insights from computational modeling
Theoretical conditions for long-lasting neuronal desynchronization in oscillatory recurrent networks with STDP
Restoration of segregated, physiological neuronal connectivity by desynchronizing deep brain stimulation |
Conference Website